2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

Product Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
CAS No.: 890842-28-1
Chemical Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Synonyms: CS-1142;GSK 650394;GSK650394 (Free base);SGK inhibitor GS650394;6-O-α-D-Glucopyranosyl-D-glucose;2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
CBNumber: CB52518968
Molecular Formula: C25H22N2O2
Formula Weight: 382.45
MOL File: 890842-28-1.mol

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Property

storage temp.: room temp
solubility: DMSO: soluble20mg/mL, clear
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0773
Product name: GSK-650394
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $150
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0773
Product name: GSK-650394
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $598
Updated: 2024/03/01

Cayman Chemical

Product number: 17001
Product name: GSK650394
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 17001
Product name: GSK650394
Purity: ≥98%
Packaging: 10mg
Price: $198
Updated: 2024/03/01

Cayman Chemical

Product number: 17001
Product name: GSK650394
Purity: ≥98%
Packaging: 25mg
Price: $467
Updated: 2024/03/01

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemical Properties,Usage,Production

Uses

GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.

Definition

ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine.

Biochem/physiol Actions

GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.

storage

Store at RT

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Suppliers

China 78 India 1 The Netherlands 1 United Kingdom 2 United States 15 Global 97

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890842-28-1, 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacidRelated Search:

GSK8612 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol 1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone GSK8612 GSK6853 GSK620 GSK591 GSK5959 ROR gamma-t-IN-1 GSK872 2-FLUOROPHENYL CYCLOPENTYL KETONE Cisplatin XL765 5-Aza-2'-deoxycytidine 2,6-PYRIDINEDIAMINE, N6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-1-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO- Veliparib Rapamycin

GSK650394 (Free base)

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

GSK 650394

SGK inhibitor GS650394

CS-1142

Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-

6-O-α-D-Glucopyranosyl-D-glucose

890842-28-1

Inhibitors